Bonjesta is a prescription medication used to treat nausea and vomiting of pregnancy, commonly known as morning sickness [1]. It is a combination of two active ingredients: doxylamine succinate and pyridoxine hydrochloride [1][2].
What is in Bonjesta and how does it work?
Bonjesta contains doxylamine succinate, an antihistamine, and pyridoxine hydrochloride, a form of vitamin B6 [1][2]. This combination is believed to work by reducing nausea and vomiting. Doxylamine succinate helps to alleviate nausea, while pyridoxine hydrochloride may also contribute to reducing nausea and vomiting symptoms [1]. The delayed-release formulation of Bonjesta is designed to provide symptom relief throughout the day [3].
How is Bonjesta different from Diclegis?
Bonjesta is a delayed-release capsule that contains the same active ingredients as Diclegis: doxylamine succinate and pyridoxine hydrochloride [2][4]. However, Bonjesta's formulation is designed to release the medication over a longer period, potentially offering extended relief compared to Diclegis [3][4].
How long does Bonjesta take to work?
The onset of action for Bonjesta can vary, but the delayed-release formulation is intended to provide continuous relief from nausea and vomiting symptoms throughout the day [3].
When does Bonjesta's patent expire?
Information on Bonjesta's specific patent expiration dates can be found on DrugPatentWatch.com [5].
What are the potential side effects of Bonjesta?
Common side effects associated with Bonjesta include drowsiness and dizziness [1][6]. It is important for individuals taking Bonjesta to avoid activities requiring mental alertness, such as driving or operating heavy machinery, until they know how the medication affects them [6]. Other reported side effects can include dry mouth, constipation, and urinary tract infection [1].
Can I take Bonjesta if I am breastfeeding?
Doxylamine succinate, one of the active ingredients in Bonjesta, can pass into breast milk. Therefore, caution is advised if breastfeeding while taking Bonjesta [1].
What clinical data supports Bonjesta's effectiveness?
Clinical studies have demonstrated the efficacy of the doxylamine succinate and pyridoxine hydrochloride combination in reducing the severity of nausea and vomiting associated with pregnancy [2].
Who manufactures Bonjesta?
Bonjesta is manufactured by Pozen Inc. [4].
Sources
1. https://www.bonjesta.com/
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627021/
3. https://www.webmd.com/drugs/2/236086/bonjesta-oral/details
4. https://www.prnewswire.com/news-releases/pozen-announces-fda-approval-of-bonjesta-delayed-release-tablets-for-nausea-and-vomiting-of-pregnancy-300244194.html
5. https://drugpatentwatch.com/
6. https://www.goodrx.com/bonjesta