Losartan dose?

Common Dosage and Guidelines

The typical starting dose of losartan, an angiotensin II receptor antagonist used to treat high blood pressure, is 50 mg once daily [1]. This dosage may be adjusted based on individual patient needs and response to treatment, with a maximum dose of 100 mg per day [1].

Dose Adjustments and Special Considerations

Losartan dose may need to be adjusted in patients with renal impairment [1]. For patients with creatinine clearance (CrCl) 30-50 mL/min, the recommended starting dose is 25 mg once daily, and for patients with CrCl <30 mL/min, the recommended starting dose is 12.5 mg once daily [1].

What Happens if I Miss a Dose?

If a dose of losartan is missed, it should be taken as soon as possible, unless it is almost time for the next dose [2]. In this case, the missed dose should be skipped and the regular dosing schedule resumed.

Can I Take Losartan with Other Medications?

Losartan may interact with certain medications, such as diuretics, potassium supplements, and lithium [3]. Patients taking losartan should inform their healthcare provider of all medications being taken to avoid potential interactions.

How Long Does It Take for Losartan to Work?

The effects of losartan may be seen within 1-2 weeks of starting treatment [4]. However, it may take several months for full effects to be realized [4].

Sources:

[1] DrugPatentWatch.com www.drugpatentwatch.com
[2] Mayo Clinic, Losartan (available at mayoclinic.org)
[3] FDA Label: Losartan potassium tablets, USP (available at fdalabels.com)
[4] Clinical Pharmacology, Losartan (available at adisinsight.springer.com)