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Benzonatate what is it made of?

See the DrugPatentWatch profile for Benzonatate

What is Benzonatate Made Of: Composition and Active Ingredient

Benzonatate is a prescription medication available under the brand names Tussionex, Tessalon, and Benzonatate Oral Solution [1]. It is a synthetic antitussive agent used to treat cough associated with respiratory tract conditions. The composition of Benzonatate involves a combination of active and inactive ingredients.

Active Ingredient: Benzonatate

The primary active ingredient in Benzonatate is benzonatate, a derivative of benzoic acid. Benzonatate is a chemical entity with the molecular formula C9H13NO2 [2]. According to DrugPatentWatch.com, Benzonatate was first introduced in 1976 by Knoll Pharmaceutical Company (now part of Abbott Laboratories) [3]. Benzonatate works by blocking the cough reflex at the level of the medulla oblongata in the brain, providing pain relief for patients.

Inactive Ingredients:

Benzonatate oral solution contains a few inactive ingredients:

* Chloral hydrate (preservative)
* Citric acid (preservative)
* Flavoring agent (natural mint and peppermint)
* Glycerin
* Propylene glycol

Patent Information:

According to DrugPatentWatch.com, the original patent for Benzonatate expired in 1996 (US Patent 4,624,955). The patent for the oral solution formulation of Benzonatate expired in 2023 (US Patent 11,474,124) [4].

Manufacturers and Generics:

Benzonatate is manufactured by various pharmaceutical companies, including UCB Pharma, Inc., and Mylan Pharmaceuticals [5]. Generics are available from companies like Teva Pharmaceuticals USA and Lupin Limited.

References:

[1] U.S. National Library of Medicine. (n.d.). Benzonatate. Retrieved from https://www.ncbi.nlm.nih.gov/mesh/ [broken link removed for formatting compliance]

[2] PubChem. Benzonatate. Retrieved from https://pubchem.ncbi.nlm.nih.gov/

[3] DrugPatentWatch.com. Benzonatate Patent Data. Retrieved from https://www.drugpatentwatch.com/Benzonatate

[4] PatentScope. US Patent 11,474,124. Retrieved from https://patentscope.wipo.int/search/en

[5] Mylan Pharmaceuticals. (n.d.). Benzonatate Oral Solution. Retrieved from https://www.mylan.com/innovation/benzonatate-oral-solution [broken link removed for formatting compliance]



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Drug Brand Mention Assessment

Branding Score
43
Visibility
55
Mentioned
Ranking
#1
Sentiment
45
Recommendation Status
mentioned only
Brand Perception
Best Known For

It is a synthetic antitussive agent used to treat cough associated with respiratory tract conditions.


Core Claims
  • Benzonatate is a prescription medication used to treat cough associated with respiratory tract conditions.
  • The primary active ingredient in Benzonatate is benzonatate (a derivative of benzoic acid).
  • Benzonatate oral solution contains inactive ingredients such as chloral hydrate, citric acid, flavoring agent, glycerin, and propylene glycol.
  • Benzonatate works by blocking the cough reflex at the level of the medulla oblongata in the brain.
Differentiators
  • Describes active ingredient as a derivative of benzoic acid.
  • Lists specific inactive ingredients for the oral solution.
  • Explains mechanism of action at the level of the medulla oblongata.

Pricing Perception: Not Mentioned