What US patent application covers vinblastine/vindoline biosynthesis?
I don’t have the specific “Google Patents” record or the exact US application number/title you mean, and I can’t search Google Patents directly from here. If you share either (1) the Google Patents link, (2) the application/publication number (e.g., US20xx/xxxxx), or (3) the assignee/inventor name, I can identify the exact claims and summarize what it covers.
What to search on Google Patents for vinblastine/vindoline biosynthesis
On Google Patents, the most common way people find this topic is to search combinations of these terms (in the title/abstract where possible):
- “vinblastine” AND (“vindoline” OR “catharanthine”)
- “vindoline biosynthesis”
- “vinblastine biosynthetic pathway”
- “monoterpene indole alkaloid” (often used as a broader class)
- “plant cell” OR “yeast” OR “engineered” AND “indole alkaloid”
- “CYP” OR “O-methyltransferase” OR “dioxygenase” plus vinblastine/vindoline (many claims cite specific enzymes)
- “BAHD” (one enzyme family frequently tied to steps in indole alkaloid modifications)
If you tell me which of these seems to match your Google Patents page (even just the assignee), I can narrow to the likely US publication.
How these applications usually describe the biosynthesis
US filings in this area typically focus on one or more of:
- Engineered microorganisms or plant-cell systems that produce vinblastine or vindoline (or direct precursors such as catharanthine/vindoline intermediates).
- Genetic constructs (genes/operons) encoding pathway enzymes for specific steps in monoterpene indole alkaloid biosynthesis.
- Methods of producing the compounds in bioreactors or transformed cells, including fermentation and purification steps.
The exact scope depends on what the claims cover (e.g., “constructs and engineered hosts” vs “methods of production” vs “specific enzyme variants”).
What the US application format will look like (so you can confirm you found the right one)
On Google Patents, US publications usually appear as:
- US20YY/NNNNNNN (published application), or
- USNNNNNNN (issued patent)
If you paste the URL, I can tell you which it is and map the publication number to the claims relevant to “biosynthesis” and “vindoline.”
If you mean “US patent application” filed by a specific company
Many of these filings are assigned to biotech or specialty pharma/ag-biotech groups working on alkaloid pathway engineering. To pinpoint the right application, I need at least one of:
- assignee name (company)
- inventor name
- the compound(s) the claims explicitly mention (vinblastine vs vindoline vs catharanthine vs intermediates)
- the publication number from the Google Patents page
Send me one detail and I’ll extract the answer you want
Reply with either the Google Patents link or the US publication/application number. Then I can summarize:
- the title and abstract in plain language,
- the key claims tied to vinblastine/vindoline biosynthesis,
- the main host system (plant vs microbial),
- and the publication/patent timeline features shown on Google Patents.
Sources: none (no specific Google Patents record or application number was provided).