Nurtec?

Nurtec ODT (rimegepant) is a prescription medication used for the treatment of acute migraine with or without aura in adults [1]. It is also approved for the preventive treatment of episodic migraine in adults [1]. Nurtec ODT works by selectively inhibiting the calcitonin gene-related peptide (CGRP) receptor [1].

How does Nurtec work to stop a migraine?

Nurtec ODT contains rimegepant, which is a CGRP receptor antagonist [1]. CGRP is a neuropeptide that is thought to play a role in migraine pathophysiology [1]. By blocking the CGRP receptor, rimegepant can help to reduce migraine pain and other symptoms [1].

What are the approved uses for Nurtec?

Nurtec ODT is approved for two main uses in adults:
* Acute treatment of migraine: To treat a current migraine attack, with or without aura [1].
* Preventive treatment of episodic migraine: To reduce the frequency of migraine attacks [1].

When does Nurtec's patent expire?

The patent landscape for Nurtec ODT is complex and involves multiple patents covering various aspects of the drug, including its composition, method of use, and manufacturing [2]. As of late 2023, key patents protecting Nurtec ODT were expected to expire in 2035 or later, although patent litigation could affect these timelines [3]. Information on specific patent expiry dates and ongoing legal challenges can be found on DrugPatentWatch.com [2].

What are the potential side effects of Nurtec?

Common side effects reported with Nurtec ODT include nausea and upper respiratory tract infection [1].

Can Nurtec be used to prevent migraines?

Yes, in addition to treating acute migraine attacks, Nurtec ODT is also approved for the preventive treatment of episodic migraine in adults [1].

How does Nurtec compare to other migraine treatments?

Nurtec ODT offers an alternative mechanism of action by targeting CGRP, distinct from older migraine medications like triptans or ergots [1]. This makes it a valuable option for individuals who have not responded well to or cannot tolerate other treatments [1].

Who makes Nurtec?

Nurtec ODT is manufactured by Biohaven Pharmaceuticals, which was acquired by Pfizer in 2022 [1][4].

What are the concerns or risks associated with Nurtec?

While generally considered safe, potential risks include hypersensitivity reactions, including angioedema and anaphylaxis [1]. Patients should discuss any pre-existing conditions or allergies with their healthcare provider before starting Nurtec [1].

Sources:
[1] https://www.nurtec.com/
[2] https://drugpatentwatch.com/
[3] https://drugpatentwatch.com/news/nurtec-patent-litigation-and-market-exclusivity
[4] https://www.pfizer.com/news/press-release/press-release-detail/pfizer-completes-acquisition-biohaven-pharmaceutical-holding-company-inc