Can you drink alcohol while taking ezetimibe?
Yes. Ezetimibe does not have a well-known, specific alcohol-drug interaction that would usually require avoiding alcohol for most people taking it.
Does alcohol change ezetimibe levels or side effects?
There’s no evidence that alcohol meaningfully changes ezetimibe levels. The main practical concern is tolerability: both alcohol and ezetimibe can contribute to gastrointestinal side effects (like nausea or stomach upset) in some people, so heavy drinking may make those symptoms more likely.
What if you have liver disease or elevated liver enzymes?
Ezetimibe can be associated with liver-related lab changes, especially when used with a statin. If you have liver disease, elevated liver enzymes, or you’re taking ezetimibe plus a statin, it’s safer to be cautious with alcohol and ask your clinician for personalized guidance.
Safety tips if you choose to drink
Stick to moderate amounts, avoid binge drinking, and stop or reduce alcohol if you notice new or worsening symptoms (especially abdominal pain, unusual fatigue, yellowing of the skin/eyes, or dark urine). If you’re taking ezetimibe with a statin, keep alcohol intake conservative and discuss safe limits with your prescriber.