What is ranitidine hydrochloride, and what is it used for?
Ranitidine hydrochloride is a medicine used to reduce stomach acid. It has been used for conditions such as heartburn (acid indigestion) and ulcers that are related to excess stomach acid.
Are ranitidine tablets still sold in the U.S.?
Ranitidine (including ranitidine hydrochloride tablets) was removed from sale in the U.S. by the FDA in 2020 due to concerns about contamination with NDMA, a probable human carcinogen. Because of that action, ranitidine is generally not available through routine retail pharmacy channels in the U.S.
Why was ranitidine recalled or removed?
The FDA’s decision was tied to findings that ranitidine could form NDMA over time, especially under certain storage conditions. That potential contamination drove the market withdrawal.
What should patients use instead of ranitidine?
Common alternatives depend on the condition being treated:
- For acid reflux/heartburn: other H2 blockers (like famotidine) may be used.
- For ulcers or stronger acid control: proton pump inhibitors (PPIs) such as omeprazole or pantoprazole are often used.
If you’re switching, the best option depends on your diagnosis, current dose, and other medicines you take.
What side effects do people report with ranitidine tablets?
Like other acid-reducing medicines, ranitidine can cause side effects such as headache, dizziness, constipation or diarrhea, and less commonly more serious reactions. If you’re experiencing new symptoms, it’s important to contact a clinician.
How do ranitidine tablets work?
Ranitidine works by blocking histamine H2 receptors on stomach cells. That reduces acid production, which helps relieve heartburn and supports ulcer healing.
What dosing forms are available (before the market withdrawal)?
Ranitidine hydrochloride was available as oral tablets and other formulations in various strengths, used for short-term relief or longer treatment for acid-related conditions.
If you tell me your country (and whether you mean adult or child dosing), I can tailor the likely current availability and the most common substitutes for your situation.