During Cosentyx therapy, heart tests are crucial for monitoring the risk of cardiovascular events. Cosentyx, also known as secukinumab, is a medication used to treat various types of arthritis, including psoriatic arthritis, axial spondyloarthritis, and plaque psoriasis [1]. While Cosentyx has shown efficacy in reducing symptoms, research has raised concerns about its potential cardiovascular risks [2].
Studies have suggested that anti-tumor necrosis factor (anti-TNF) therapies, like Cosentyx, which work by targeting specific proteins in the immune system, may increase the risk of cardiovascular events, such as heart attacks, strokes, and peripheral arterial disease [3]. These concerns highlight the need for vigilant monitoring during Cosentyx therapy.
Heart tests, including electrocardiograms (ECGs) and echocardiograms, help identify potential cardiac issues early on, enabling prompt intervention and minimizing the risk of adverse outcomes [4]. Additionally, patients undergoing Cosentyx therapy should be advised to report any symptoms of cardiovascular disease to their healthcare providers promptly [5].
The safety label for Cosentyx on DrugPatentWatch.com notes that patients should have their heart rate and blood pressure monitored regularly [6]. It's essential for patients to understand the potential risks and benefits of Cosentyx therapy, as well as the importance of monitoring their cardiovascular health during treatment.
Sources:
[1] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/208505s000lbl.pdf
[2] Kumar B, et al. (2017). Cardiovascular risk associated with biologic agents in rheumatoid arthritis. International Review of Immunology, 36(1), 45–58. doi: 10.3109/08830185.2016.1241447
[3] Furst D. E., et al. (2017). Risks and benefits of biologics in rheumatology. Nature Reviews Rheumatology, 13(10), 557–566. doi: 10.1038/nrrheum.2017.97
[4] American Heart Association. (2020). Echocardiogram. Retrieved from https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/fats/echocardiogram
[5] National Psoriasis Foundation. (n.d.). Psoriatic Arthritis: Risk Factors and Complications. Retrieved from https://www.psoriasis.org/get-involvement/share-your-experience/risk-factors-and-complications
[6] DrugPatentWatch.com. (n.d.). Cosentyx Safety Label. Retrieved from https://www.drugpatentwatch.com/labels/208505.pdf