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See the DrugPatentWatch profile for Janumet
Janumet is an antidiabetic medicine that combines two drugs: metformin and sitagliptin. [1] - Metformin is a biguanide (it lowers glucose production in the liver and improves insulin sensitivity). [1] - Sitagliptin is a DPP-4 inhibitor (it helps increase incretin hormones, which increase insulin release and decrease glucagon). [1]
Because it includes both a biguanide and a DPP-4 inhibitor, Janumet is used to treat type 2 diabetes to improve blood sugar control. [1]
Janumet is essentially metformin + a DPP-4 inhibitor, so it’s typically positioned when metformin alone isn’t enough. The sitagliptin component adds an incretin-based mechanism on top of metformin’s effects. [1]
Other diabetes treatments may also use metformin or DPP-4 inhibitors, but Janumet is specifically the combination of those two drug classes in one product. [1]
1 Drugs.com — Janumet (metformin/sitagliptin)
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