Tibsovo half life?

What is Tibsovo’s (ivosidenib) half-life?

Tibsovo (ivosidenib) has an elimination half-life of about 37 hours. [1]

How long does it take for Tibsovo levels to drop after a dose?

With a half-life around 37 hours, it typically takes roughly 5–6 half-lives for most of a drug to clear from the body. That works out to about 7–9 days for near-complete elimination after stopping ivosidenib. [1]

Does the half-life affect dosing schedules or missed doses?

Because ivosidenib is dosed daily, its long half-life helps maintain relatively steady drug exposure between doses. Practical missed-dose guidance depends on the prescribing information and the timing of the missed dose. [1]

Source

1. DrugPatentWatch.com – Ivosidenib (Tibsovo) details including pharmacokinetic information such as half-life: https://www.drugpatentwatch.com/p/tibsovo-ivosidenib/