Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. It belongs to a class of drugs called statins. When taking Lipitor, it is important to be aware of potential drug interactions, including interactions with pain relievers.

According to drugs.com, acetaminophen (the active ingredient in Tylenol) is generally considered safe to take with Lipitor [2]. However, it is always important to consult with a healthcare provider before taking any new medication or combination of medications.

It is also important to note that nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen can interact with Lipitor and increase the risk of side effects such as muscle damage and kidney problems [3]. Therefore, it is generally recommended to avoid taking NSAIDs while on Lipitor.

In summary, acetaminophen (Tylenol) is generally considered safe to take with Lipitor, but it is important to consult with a healthcare provider before taking any new medication or combination of medications. NSAIDs such as ibuprofen and naproxen should generally be avoided while on Lipitor.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/drug-interactions/atorvastatin-with-tylenol-276-0-11-12.html
[3] https://www.webmd.com/drugs/2/drug-3330/lipitor-oral/details