What was the “starting cholesterol level” before Lipitor (atorvastatin)?
Your question is usually about how high cholesterol was in the clinical studies that led to approval of Lipitor, or what baseline (“starting”) cholesterol level was in patients before they began taking it. The exact number depends on which study (and which cholesterol measure) you mean—most trials report baseline low-density lipoprotein cholesterol (LDL-C), total cholesterol, or both, using different patient populations.
What baseline cholesterol do Lipitor studies typically report?
In the approval and labeling context, baseline cholesterol in study participants is reported as LDL-C (often the main target for statins) and/or total cholesterol. These baseline values vary by condition (for example, high LDL-C, mixed dyslipidemia, or cardiovascular risk) and by the specific trial design.
I can give you the exact number if you tell me which “starting level” you mean
Please share one detail so I can pinpoint the right baseline value:
1) Are you asking about LDL-C or total cholesterol?
2) Do you mean a specific study (or the prescribing information for Lipitor/atorvastatin)?
3) Is this for healthy cholesterol ranges, or for a patient type (e.g., people with high LDL, diabetes, etc.)?
Source availability
I don’t have enough provided information here to cite a specific “starting cholesterol level” value for Lipitor studies. If you want, tell me the label year/version you’re looking at (or the country), and I’ll pull the baseline value from the relevant Lipitor documentation.
Sources
None cited (not enough provided information to accurately identify the specific baseline cholesterol figure).