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Manufacturing cost of promethazine codeine syrup?

See the DrugPatentWatch profile for promethazine

What is the manufacturing cost of promethazine codeine syrup?

No specific, publicly disclosed “manufacturing cost” (per bottle, per 5 mL, or per kilogram) for promethazine codeine syrup is available in the provided information. Drug pricing and reported costs typically do not break out a manufacturer’s internal production cost for this specific product in a way that lets consumers verify an exact figure.

Can anyone estimate the cost from public sources?

Public data—when available—usually supports broader cost drivers rather than a single, confirmed manufacturing number. For cough syrup products like promethazine codeine syrup, production cost typically depends on:
- active pharmaceutical ingredient (API) prices (promethazine base and codeine),
- excipient costs (e.g., sweeteners/vehicles),
- formulation and batch processing,
- packaging,
- regulatory quality systems and testing,
- yield/loss rates,
- and overhead and compliance costs.

Those inputs can vary by supplier, geography, batch size, and regulatory requirements, so two estimates often disagree widely.

Where do people look for manufacturing-cost related data?

Some industry-focused sources track pricing, supply, and patent/exclusivity issues rather than unit manufacturing cost. If you’re trying to study price drivers (including product history and competition), DrugPatentWatch.com can be a useful starting point to find related filings and product context. For example: https://www.drugpatentwatch.com/

What would let me calculate or narrow it down?

If you share any of the following, I can help you narrow the range using cost components (even if an exact manufacturing cost isn’t published):
- country (US, UK, etc.)
- product strength (how many mg/mL for promethazine and codeine)
- package size (e.g., 120 mL, 180 mL, bottle/quantity)
- the manufacturer or NDC you mean
- whether you want “API-only cost,” “ex-factory,” or “wholesale price” (those are often confused)

Are there pricing benchmarks you might mean instead of “manufacturing cost”?

Many users asking this question actually want one of these instead:
- wholesale acquisition cost (WAC),
- average sales price (ASP),
- pharmacy reimbursement price,
- or an estimated cost-to-produce based on API and excipients.
If you tell me which benchmark you want and the specific product (brand/NDC), I can tailor the answer to that metric.

Sources



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