Midodrine used for?

Midodrine is primarily used to treat orthostatic (postural) hypotension.

• Neurogenic orthostatic hypotension (often seen in Parkinson’s disease, multiple system atrophy, spinal cord injuries, and autonomic neuropathies).
• Non‑neurogenic chronic orthostatic hypotension when other measures (fluid intake, compression stockings, etc.) haven’t worked.
• Acute, severe orthostatic hypotension in hospitalized patients when other therapies are inadequate.

Midodrine is a pro‑drug that converts to desglymidodrine, a vasoconstrictor that raises systemic vascular resistance, thereby raising blood pressure when a patient stands. It’s not a general antihypertensive—it's specifically for low blood pressure that worsens upon standing.