What is US7803839B2, and where does cobimetinib appear?
US7803839B2 is a U.S. patent that includes cobimetinib-related chemical matter and/or preparation routes in its disclosure. The exact “synthesis steps” depend on which example (compound/step numbering) you mean, because patents typically provide multiple embodiments (different starting materials, intermediates, or final salt forms).
How do I find the exact cobimetinib synthesis steps in US7803839B2?
To extract the synthesis “steps” precisely, you need to locate the relevant portions of the patent:
- The examples section (often where each step is numbered from preparation of an intermediate to final conversion).
- Any “Scheme” drawings (patent schematics usually map step numbers to reagents/conditions).
- The compound table or specific example listing for cobimetinib (and possibly cobimetinib fumarate or other salts).
If you paste the specific example number(s) or the scheme you’re interested in (or the relevant text from the patent), I can rewrite it into a clean, step-by-step sequence (reactant → conditions → product at each step) using only what’s actually stated in the document.
Can I list cobimetinib step-by-step from US7803839B2 without seeing the patent text?
Not reliably. Patent synthesis sequences are highly example-specific (step order, equivalents, solvents, temperatures, workups, purification, and yields), and giving steps without confirming the exact example would risk being inaccurate.
What details should you provide so I can turn it into “synthesis steps”?
Send any one of the following:
- The patent page text for the cobimetinib example (or screenshots).
- The example number (e.g., “Example 12”) and the scheme identifier.
- The claims or “preparation” subsection heading that mentions cobimetinib.
Then I’ll produce a concise “Step 1 / Step 2 / …” synthesis outline matching the patent.
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Source
- https://patents.google.com/patent/US7803839B2/en