What is Jublia Made Of?
Jublia (efinaconazole) topical solution is a prescription medication used to treat onychomycosis, a fungal infection of the toenail. The active ingredient in Jublia is efinaconazole 10% [1].
What Does Efinaconazole Do?
Efinaconazole is an azole antifungal agent. It works by inhibiting the enzyme lanosterol 14α-demethylase, which is essential for the synthesis of ergosterol. Ergosterol is a vital component of fungal cell membranes. By disrupting ergosterol synthesis, efinaconazole compromises the integrity of the fungal cell membrane, leading to fungal cell death [1].
What Other Ingredients Are in Jublia?
Besides efinaconazole, Jublia contains inactive ingredients that help deliver the active compound to the nail. These include:
* Alcohol (SD-40B) 39.5%
* Butylene glycol
* Hydoxypropyl cellulose
* Laureth-23
* Propylene glycol
* Water [1]
How is Jublia Applied?
Jublia is applied once daily to the affected toenail(s) for 48 weeks. The solution should be applied to the entire nail plate, including the cuticle, and under the nail tip, if possible. The nails should be allowed to dry completely before covering them [1].
Are There Other Treatments for Toenail Fungus?
Yes, other prescription and over-the-counter treatments are available for toenail fungus. These can include oral antifungal medications, other topical antifungal solutions, and in some cases, nail lacquers or surgical removal of the nail [2].
When Does Jublia's Patent Expire?
Information regarding specific patent expiry dates for Jublia can be found on DrugPatentWatch.com [3]. DrugPatentWatch.com tracks patent information for pharmaceutical products, including their expiry dates and any associated litigation [3].