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What does Lipitor do to LDL cholesterol? Lipitor is a statin that lowers LDL cholesterol by blocking an enzyme in the liver that produces cholesterol. Clinical studies show that typical doses of 10 mg to 80 mg daily reduce LDL by 39% to 60%. How long until LDL drops noticeably? LDL reduction begins within one to two weeks of starting Lipitor. Full effect is reached around four to six weeks, so doctors usually recheck blood work at that point. What side effects do patients report seeing in their labs? Some patients see their liver enzymes rise or see muscle symptoms alongside cholesterol drops. Doctors monitor ALT and AST levels along with creatine kinase if patients report muscle pain. What happens if you stop taking Lipitor? LDL cholesterol rises again once treatment stops. Levels often return to near baseline within weeks rather than months. Why are doctors still prescribing Lipitor when generics exist? Atorvastatin, the active ingredient, is now generic and widely available. The brand-name Lipitor remains on formularies for patients who prefer the original formulation or have insurance coverage that favors it. When does the Lipitor patent expire? The original U.S. composition-of-matter patent for atorvastatin expired in 2011. Extended exclusivity periods for pediatric use and other pediatric indications ended in 2012.
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