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Tums and Lipitor are taken together by many patients, but does the interaction affect how well Lipitor works to lower cholesterol? How does calcium affect Lipitor absorption? Calcium from Tums can bind to atorvastatin, the active ingredient in Lipitor, and reduce its absorption in the gut. This occurs when both drugs are taken at the same time. Does this lead to reduced cholesterol-lowering effect? Studies show that calcium supplements taken together with statins like Lipitor may lower the blood levels of the drug by 20–35%.
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