According to sources [2] and [3], it is generally not recommended to take Advil (ibuprofen) with antidepressants, such as Zoloft (sertraline), due to the potential for adverse interactions. Both Advil and antidepressants can increase the risk of bleeding, and taking them together may increase this risk even further. Additionally, some antidepressants can inhibit the liver enzymes responsible for metabolizing Advil, leading to increased levels of the drug in the body and potential toxicity.

However, the severity of these interactions can vary depending on the individual and the specific medications involved. In some cases, a healthcare provider may determine that the benefits of taking both medications outweigh the risks. It is important to always consult with a healthcare provider before taking any new medications, including over-the-counter pain relievers like Advil, especially if you are already taking antidepressants.

Source [1] provides information on the patent status of Advil and is not relevant to the question at hand.

Sources:
[2] https://www.singlecare.com/blog/ibuprofen-and-zoloft/
[3] https://www.health.harvard.edu/press_releases/caution-popular-painkillers-may-interfere-with-antidepressants.