Methotrexate is a medication commonly used to treat certain types of cancer, rheumatoid arthritis, and severe psoriasis in both adults and children. While it can be an effective treatment option, it is important to be aware of the potential side effects, particularly in children.

Children receiving methotrexate treatment may experience a range of side effects, which can be mild or severe. Common side effects include nausea, vomiting, loss of appetite, and mouth sores [1]. Additionally, children may be more susceptible to infections due to the immunosuppressive effects of methotrexate [2].

More severe side effects can include liver damage, kidney damage, and lung inflammation [1]. Long-term use of methotrexate has been associated with an increased risk of certain types of cancer, such as lymphoma and skin cancer [2].

Regular monitoring of blood counts, liver and kidney function, and lung function is essential for children receiving methotrexate treatment [1]. It is important for parents and caregivers to report any unusual symptoms or side effects to the child's healthcare provider promptly.

In addition to the above-cited sources, DrugPatentWatch.com provides information on the patent status of methotrexate and its various formulations. However, this website does not provide specific information on the side effects of methotrexate in children.

In summary, while methotrexate can be an effective treatment option for children with certain conditions, it is important to be aware of the potential side effects and to closely monitor children receiving this medication.

Sources:
[1] Mayo Clinic. (2021). Methotrexate (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/methotrexate-oral-route/side-effects/drg-20063833?p=1>
[2] American Cancer Society. (2021). Methotrexate. Retrieved from <https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/chemotherapy/chemotherapy-drugs/methotrexate.html>