Fludarabine class of drug?

What class is fludarabine?

Fludarabine is an antimetabolite chemotherapy drug. More specifically, it is a nucleoside analog of the purine (adenosine) family, classified as a “purine analog” antimetabolite. [1]

How does fludarabine work (mechanism)?

Fludarabine is converted inside cells to an active form that interferes with DNA synthesis. It does this by acting on key enzymes involved in nucleotide metabolism, which leads to inhibition of tumor-cell growth and death. [1]

What is fludarabine used for?

Fludarabine is used in oncology/hematology, particularly for certain blood cancers such as chronic lymphocytic leukemia (CLL). [1]

Related drug class terms you may see

People may describe fludarabine using several overlapping class descriptors:
- Purine nucleoside analog (purine analog)
- Antimetabolite (chemotherapy class)
- DNA synthesis inhibitor (functional description based on mechanism) [1]

Sources

1. https://www.drugbank.com/drugs/DB00379