Prolonged use of Cosentyx (secukinumab) has been associated with certain complications. According to Drug Patent Watch, adverse effects reported include infections, allergic reactions, and potential effects on liver enzymes. Additionally, a study published in the National Center for Biotechnology Information highlights potential side effects such as upper respiratory tract infections, inflammatory bowel disease, and Candida infections. The Mayo Clinic lists common side effects of Cosentyx as upper respiratory infections, diarrhea, and reactions at the injection site. It is important for patients using Cosentyx to be aware of these potential complications and consult with their healthcare provider if any concerning symptoms arise.

Sources:
[1] https://www.drugpatentwatch.com/p/biologics/tradename/COSENTYX
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695424/
[3] https://www.mayoclinic.org/drugs-supplements/secukinumab-intravenous-route-subcutaneous-route/side-effects/drg-20137344?p=1