There is no definitive evidence to suggest that broccoli interferes with Lipitor (atorvastatin), a medication used to treat high cholesterol levels. However, it is always recommended to consult with a healthcare provider or pharmacist regarding potential interactions between food and medications.

Broccoli is a nutrient-dense vegetable rich in vitamins, minerals, and antioxidants. It belongs to the Brassica family, which also includes other cruciferous vegetables like cauliflower, kale, and Brussels sprouts. These vegetables are known for their health benefits, including potential cancer-preventive properties [1].

Lipitor, a statin drug, works by inhibiting the HMG-CoA reductase enzyme, which plays a crucial role in cholesterol production in the body. This results in reduced LDL (bad) cholesterol levels and increased HDL (good) cholesterol levels [2].

While some medications may interact with specific foods, there is no evidence suggesting that broccoli or other cruciferous vegetables have a direct interaction with Lipitor or other statin drugs [3]. Nonetheless, it is essential to maintain a balanced and varied diet while taking any medication.

In summary, based on the available information, there is no evidence to suggest that broccoli interferes with Lipitor. However, it is always advisable to consult a healthcare professional regarding potential food-drug interactions.

Sources:

1. "Broccoli, raw." National Institutes of Health (NIH). U.S. Department of Health and Human Services, 11 Feb. 2021, https://fdc.nal.usda.gov/fdc-app.html#/food-details/169344/nutrients.
2. "Atorvastatin." MedlinePlus, U.S. National Library of Medicine, 11 Feb. 2021, https://medlineplus.gov/druginfo/meds/a601262.html.
3. "Food-Drug Interactions." DrugPatentWatch, 2021, https://drugpatentwatch.com/resources/food-drug-interactions.