Advil is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce inflammation. According to Drug Patent Watch [1], the active ingredient in Advil is ibuprofen. Xarelto is a blood thinner that is used to prevent blood clots. Health Harvard [2] warns that taking NSAIDs, such as Advil, with blood thinners like Xarelto can increase the risk of bleeding.

The combination of blood thinners and NSAIDs can cause bleeding because both drugs affect blood clotting. Blood thinners like Xarelto reduce the blood's ability to clot, while NSAIDs like Advil can interfere with platelets, which are blood cells that help the blood clot. When these drugs are taken together, the risk of bleeding increases significantly.

Mayo Clinic [3] suggests that patients who are taking blood thinners should avoid taking NSAIDs unless they are prescribed by a doctor. If NSAIDs are necessary, the patient should be monitored closely for signs of bleeding, such as unusual bruising, bleeding gums, or nosebleeds.

In conclusion, taking Advil with Xarelto can increase the risk of bleeding. Patients who are taking blood thinners should avoid taking NSAIDs unless they are prescribed by a doctor. If NSAIDs are necessary, the patient should be monitored closely for signs of bleeding.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.health.harvard.edu/diseases-and-conditions/bad-mix-blood-thinners-and-nsaids
[3] https://www.mayoclinic.org/diseases-conditions/heart-disease/in-depth/daily-aspirin-therapy/art-20046797