See the DrugPatentWatch profile for lyrica
Can Lyrica (pregabalin) cause a low heart rate?
Lyrica (pregabalin) can affect the nervous system and may rarely be linked to heart rhythm or rate problems. Because pregabalin’s effects can vary by person and by dose, low heart rate (bradycardia) is something to consider, especially if it starts after beginning Lyrica or after a dose increase.
What symptoms should you watch for if your heart rate drops?
If Lyrica is contributing to a slower heart rate, people may notice symptoms such as dizziness, fainting or near-fainting, unusual tiredness, weakness, shortness of breath, chest discomfort, or feeling like the heart is beating too slowly. Any fainting, chest pain, severe shortness of breath, or confusion warrants urgent evaluation.
Who is more likely to develop bradycardia on Lyrica?
Risk can be higher if you already have a heart rhythm problem, conduction issues, or low baseline heart rate. It can also be more likely if Lyrica is combined with other medicines that slow heart rate, such as certain beta-blockers or some calcium channel blockers, or if you have electrolyte problems or dehydration that predispose to rhythm instability.
How quickly could it happen after starting Lyrica?
Heart-rate effects, if they occur, can appear after starting the medication or after a dose change. If you notice a clear timing link to when you began Lyrica or increased your dose, that pattern is important to report to your clinician.
What should you do if you think Lyrica is lowering your heart rate?
Check your pulse and consider getting an ECG if you have symptoms or consistently low readings. Don’t stop Lyrica suddenly without medical guidance, but contact your prescriber promptly for advice on whether the dose should be reduced, whether another cause should be evaluated, or whether a different treatment is needed.
When is it an emergency?
Seek emergency care if low heart rate comes with fainting, severe dizziness, chest pain, trouble breathing, or if you have a very slow pulse with feeling unwell. These can signal clinically significant rhythm problems rather than a mild medication side effect.
Ask your doctor the right follow-up questions
You can ask whether your specific dose and your current heart medications could interact, whether you should get an ECG or monitor your pulse at home, and what warning symptoms should trigger urgent care.
Sources
No sources were provided with your question, so I can’t cite specific clinical references here. If you share the exact Lyrica label text you’re looking at (or a link), I can confirm whether bradycardia/low heart rate is listed and how it’s described.