Meclizine is available over-the-counter (OTC) for the prevention and treatment of nausea, vomiting, and dizziness associated with motion sickness [1]. It is also used to treat vertigo, a sensation of spinning, which can be caused by inner ear problems [2].
How Does Meclizine Work for Motion Sickness?
Meclizine is an antihistamine that works by blocking the action of histamine, a chemical in the body that can trigger nausea and vomiting [1]. It is thought to affect the vomiting center in the brain and the vestibular apparatus in the inner ear, which is responsible for balance [3].
What Other Conditions Can Meclizine Treat?
Beyond motion sickness, meclizine is also prescribed to manage vertigo and dizziness caused by conditions affecting the inner ear, such as Meniere's disease [2].
How Long Does Meclizine Take to Work?
Meclizine typically begins to work about one hour after administration [1]. For motion sickness, it is often recommended to take the medication 30 minutes to 1 hour before travel [4].
What Are the Side Effects of Meclizine?
Common side effects of meclizine can include drowsiness, dry mouth, and blurred vision [1]. Less common side effects may involve fatigue, nervousness, or vomiting [5].
Are There Other Medications for Motion Sickness?
Other medications used for motion sickness include dimenhydrinate and scopolamine [6]. Dimenhydrinate is another antihistamine, while scopolamine is an anticholinergic medication often delivered via a patch placed behind the ear [7].
When Does the Patent for Meclizine Expire?
Meclizine is a long-established medication, and its original patents have long since expired, allowing for its widespread availability as a generic drug [8].
Who Manufactures Meclizine OTC Products?
Multiple pharmaceutical companies manufacture and distribute meclizine products under various brand names and as generic options available in pharmacies and retail stores [9].
Is Meclizine Safe for Children?
The safety and efficacy of meclizine have not been established in children under 12 years of age for motion sickness, and specific pediatric dosing recommendations should be followed if used [4]. Always consult a healthcare professional before giving any medication to a child.
What Is the Dosage for Meclizine?
For motion sickness in adults, the usual OTC dose is 25 mg to 50 mg taken once daily [1]. For vertigo, a healthcare provider may recommend a different dosage and frequency [2].
Can Meclizine Cause Drowsiness?
Yes, drowsiness is a common side effect of meclizine [1]. Individuals taking the medication should exercise caution when driving or operating machinery until they know how it affects them [5].
Sources:
[1] https://www.drugpatentwatch.com/meclizine
[2] https://www.drugpatentwatch.com/drug/meclizine
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990702
[4] https://www.nhs.uk/medicines/meclozine/
[5] https://www.nhs.uk/medicine-guides/pages/Interaction.aspx?file=22010
[6] https://www.nhs.uk/medicines/travel-sickness/
[7] https://www.nhs.uk/medicines/scopolamine/
[8] https://www.drugpatentwatch.com/blog/understanding-drug-patents-and-exclusivity
[9] https://www.drugpatentwatch.com/meclizine/manufacturers