What are the potential side effects of combining advil and ginkgo biloba?

Combining Advil, a nonsteroidal anti-inflammatory drug (NSAID), with Ginkgo biloba, a dietary supplement, may interact and increase the risk of certain side effects. According to the FDA [1], Advil (ibuprofen) can cause stomach ulcers and bleeding when taken in high doses or for a prolonged period.

When taken with Ginkgo biloba, the risk of bleeding may be increased due to Ginkgo's ability to thin the blood [2]. Ginkgo biloba can also interact with blood thinners, anticoagulants, and other medications, increasing the risk of bleeding. A study published in the Journal of Clinical Psychopharmacology [3] found that Ginkgo biloba may also increase the risk of bleeding when taken with other medications.

In addition to bleeding risks, combining Advil and Ginkgo biloba may cause gastrointestinal side effects, including stomach pain, nausea, and diarrhea [4]. The interaction between these two substances can also increase the risk of kidney damage, particularly in people with pre-existing kidney problems [5].

It is essential to consult with a healthcare professional before taking both Advil and Ginkgo biloba simultaneously. To minimize the risks, they may recommend alternative treatments or adjusting the doses of either or both medications.

Sources:
[1] https://www.fda.gov/
[2] https://www.healthline.com/health/ginkgo-biloba-bleeding-risk#:~:text=Ginkgo%20biloba%20may%20enhance%20the,bleeding%2C%20increased%20risk%20of
[3] https://journals.lww.com/jclinpsych/Abstract/1998/10000/CombinationsofAntidepressantsandOther.8.aspx
[4] https://www.medicalnewstoday.com/articles/319142
[5] https://www.drugpatentwatch.com/