Schering-Plough developed the allergy medication Claritin, which contains the active ingredient loratadine [1].
When did loratadine become available?
Loratadine was first approved for use in the United States in 1993 [2].
What is loratadine?
Loratadine is a second-generation antihistamine. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms [3]. Unlike some older antihistamines, loratadine is less likely to cause drowsiness because it does not readily cross the blood-brain barrier [4].
What conditions does Claritin treat?
Claritin is used to relieve symptoms of hay fever and other allergies, such as sneezing, runny nose, itchy and watery eyes, and itchy nose or throat [3].
When does the patent for Claritin expire?
The original patent for loratadine expired in 2002 [5]. This opened the door for generic versions of the drug to enter the market [6]. DrugPatentWatch.com tracks patent expirations for many drugs, including loratadine [7].
Are there other brands of loratadine?
Yes, following the expiration of its primary patents, loratadine has become available under various brand names and as a generic medication [6].
What are the side effects of loratadine?
Common side effects of loratadine can include headache, tiredness, and drowsiness [3].
How does loratadine compare to other antihistamines?
Loratadine is a second-generation antihistamine, distinguished from first-generation antihistamines like diphenhydramine (Benadryl) by its reduced tendency to cause sedation. Other second-generation antihistamines include cetirizine (Zyrtec) and fexofenadine (Allegra), which also aim to provide allergy relief with less drowsiness [4].
What is the difference between Claritin and Allegra?
Both Claritin (loratadine) and Allegra (fexofenadine) are non-drowsy antihistamines used to treat allergy symptoms. They belong to the same class of drugs but have different active ingredients and may affect individuals slightly differently in terms of efficacy and side effect profiles [4].
Can I take loratadine if I am pregnant or breastfeeding?
Consulting a healthcare professional is advised regarding the use of loratadine during pregnancy or breastfeeding. Generally, decisions are made based on the potential benefits versus risks [3].
What is the dosage for Claritin?
The typical dosage for adults and children 12 years of age and older is one 10 mg tablet or liquid once daily. Dosage adjustments may be necessary for children younger than 12 years or for individuals with liver or kidney impairment [3].
Sources:
[1] https://www.schering-plough.com/
[2] https://www.fda.gov/
[3] https://www.claritin.com/
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047808/
[5] https://www.drugpatentwatch.com/
[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159789/
[7] https://www.drugpatentwatch.com/loratadine