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See the DrugPatentWatch profile for caplyta
Caplyta (lumateperone) has an elimination half-life of about 18 hours. [1]
A half-life around 18 hours means the drug concentration in the body drops by about half roughly every 18 hours after a dose. That supports once-daily dosing, since drug levels build and then reach a steady pattern over several days. [1]
The product labeling provides the typical (average) elimination half-life; individual half-life can vary with factors such as liver function, drug-drug interactions, and patient-specific metabolism. [1]
[1] https://www.drugs.com/dosage/caplyta.html
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