See the DrugPatentWatch profile for ibsrela
Ibsrela, also known as filgotinib, is a medication taken orally [1]. It is prescribed for adults with moderately to severely active ulcerative colitis who have had an inadequate response or intolerance to conventional therapy [1]. The recommended starting dose is 100 mg once daily [1]. In some cases, the dose may be increased to 200 mg once daily [1].
How often should I take ibsrela?
Ibsrela is typically taken once daily [1]. The dosage regimen will be determined by a healthcare professional based on the individual patient's condition and response to treatment [1].
What is the recommended starting dose for ibsrela?
The recommended starting dose for ibsrela (filgotinib) is 100 mg taken by mouth once per day [1].
Can the dose of ibsrela be adjusted?
Yes, the dose of ibsrela can be adjusted. For some patients, the dose may be increased to 200 mg once daily, as advised by their doctor [1].
What is ibsrela used to treat?
Ibsrela is indicated for the treatment of adults with moderately to severely active ulcerative colitis [1]. This is for patients who have not responded adequately to or are intolerant of conventional therapies [1].
What are the potential risks or side effects of ibsrela?
Ibsrela carries a boxed warning for serious infections, including tuberculosis, and the risk of mortality, cardiovascular events, thrombosis, and malignancy [1]. Patients should be screened for tuberculosis before initiating treatment and monitored for signs of infection during treatment [1]. Other potential side effects include herpes zoster, headache, nausea, and upper respiratory tract infections [1]. The full prescribing information provides a comprehensive list of risks and side effects [1].
How does ibsrela work?
Ibsrela is a Janus kinase (JAK) inhibitor [1]. It works by selectively inhibiting JAK1, an enzyme involved in the signaling pathways of certain inflammatory cytokines that play a role in ulcerative colitis [1]. By blocking these pathways, ibsrela helps to reduce inflammation in the gut [1].