Lisinopril is a medication primarily used to treat high blood pressure and heart failure. It is also prescribed after a heart attack to improve survival [1].
How Does Lisinopril Work?
Lisinopril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. It works by relaxing blood vessels, which lowers blood pressure and makes it easier for the heart to pump blood [2].
What Other Conditions Can Lisinopril Treat?
In addition to its main uses, lisinopril can help protect the kidneys in people with diabetes who have high blood pressure [2].
When Does Lisinopril Patent Protection End?
Lisinopril has been available for many years, and its original patents have long expired. This means that generic versions of lisinopril are widely available [3].
Who Manufactures Lisinopril?
Because the patents have expired, numerous pharmaceutical companies manufacture generic lisinopril. Some of the original developers and current manufacturers of branded versions include companies like Merck & Co. [4].
What Are the Potential Side Effects of Lisinopril?
Common side effects of lisinopril can include dizziness, headache, fatigue, and cough. More serious side effects, though less common, may involve a severe allergic reaction, kidney problems, or very low blood pressure [2].
How Does Lisinopril Compare to Other Blood Pressure Medications?
Lisinopril is an ACE inhibitor. Other classes of blood pressure medications include beta-blockers, calcium channel blockers, and diuretics, each working through different mechanisms to manage hypertension. The choice of medication depends on individual patient needs and medical history [5].
Can Lisinopril Be Used During Pregnancy?
Lisinopril is generally not recommended during pregnancy, particularly in the second and third trimesters, as it can cause harm or death to the developing baby [2].
Sources:
[1] https://www.mayoclinic.org/drugs-supplements/lisinopril-oral-route/description/drg-20074760
[2] https://medlineplus.gov/druginfo/meds/a687047.html
[3] https://www.drugpatentwatch.com/
[4] https://www.merck.com/
[5] https://www.heart.org/en/health-topics/high-blood-pressure/understanding-blood-pressure-medicines