Based on the information provided, it is strongly recommended that you consult with a healthcare professional before combining Advil (ibuprofen) and antidepressants.

Advil, a common brand name for ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and fever [1]. Antidepressants, on the other hand, are prescribed to manage depression and anxiety disorders, among other mental health conditions [2].

Combining certain medications, such as NSAIDs and antidepressants, can lead to increased risks of adverse effects due to potential drug interactions [3]. For instance, combining NSAIDs with selective serotonin reuptake inhibitors (SSRIs), a common type of antidepressant, may increase the risk of gastrointestinal bleeding [3].

Therefore, it is crucial to consult a doctor or pharmacist to ensure the safety and effectiveness of combining Advil and antidepressants [3]. They can provide guidance on potential drug interactions, appropriate dosages, and alternative pain management options [4].

Sources:

[1] <https://www.drugpatentwatch.com/p/tradename/ADVIL>
[2] <https://www.nhs.uk/mental-health/talking-therapies-medicine-treatments/medicines-and-psychiatry/antidepressants/considerations/>
[3] <https://www.beaumont.org/health-wellness/blogs/alternatives-for-managing-pain-that-arent-opioids>
[4] <https://www.nhs.uk/medicines/ibuprofen/>