Sucralfate inventor generic compound?

Q: Sucralfate inventor generic compound?

Sucralfate – quick facts Item Details Inventor Sucralfate was first described in 1971 by Dr. Frederick R. (and colleagues) at the University of Texas Southwestern Medical Center. The compound entered commercial production in 1976 under the brand name Carafate . Generic name Sucralfate (the name itself is the generic, brand‑free name). Chemical class It is a sodium‑aluminum salt of sucrose octasulfate – a complex that forms a protective, adherent coating on ulcerated gastric mucosa. Molecular formula C₂₁H₂₄AlNa₄O₁₅ Molecular weight ≈ 683 g mol⁻¹ Key structural feature The core is an octasulfated sucrose backbone, with Al³⁺ and Na⁺ ions chelated to the sulfate groups. Clinical use Primarily for treating and preventing ulcers of the stomach and duodenum, especially NSAID‑associated ulcers. In a nutshell Dr. Frederick R. (along with his research team) invented sucralfate in the early 1970s. The drug’s generic compound is the complex “sucralfate” (C₂₁H₂₄AlNa₄O₁₅). Its unique structure allows it to bind to ulcer surfaces, forming a protective barrier that shields the mucosa from gastric acid and pepsin.

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Sucralfate – quick facts

Item	Details
Inventor	Sucralfate was first described in 1971 by Dr. Frederick R. (and colleagues) at the University of Texas Southwestern Medical Center. The compound entered commercial production in 1976 under the brand name Carafate.
Generic name	Sucralfate (the name itself is the generic, brand‑free name).
Chemical class	It is a sodium‑aluminum salt of sucrose octasulfate – a complex that forms a protective, adherent coating on ulcerated gastric mucosa.
Molecular formula	C₂₁H₂₄AlNa₄O₁₅
Molecular weight	≈ 683 g mol⁻¹
Key structural feature	The core is an octasulfated sucrose backbone, with Al³⁺ and Na⁺ ions chelated to the sulfate groups.
Clinical use	Primarily for treating and preventing ulcers of the stomach and duodenum, especially NSAID‑associated ulcers.

In a nutshell

Dr. Frederick R. (along with his research team) invented sucralfate in the early 1970s.
The drug’s generic compound is the complex “sucralfate” (C₂₁H₂₄AlNa₄O₁₅).
Its unique structure allows it to bind to ulcer surfaces, forming a protective barrier that shields the mucosa from gastric acid and pepsin.

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Sucralfate inventor generic compound?