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See the DrugPatentWatch profile for Dorzolamide

Dorzolamide (API) – General Pricing Snapshot

Item Typical Range (USD) Notes
Purity ≥ 98 % $1,800 – $3,200 per kg Most common grade used for ophthalmic formulations.
Purity ≥ 99 % $2,200 – $3,800 per kg Slightly higher purity for high‑end or generic drug production.
Bulk (≥ 97 %) $1,500 – $2,400 per kg Often sold to contract‑manufacturers or research labs.

These figures are rough ball‑park values gathered from a mix of public quotations, industry forums, and supplier catalogs. Actual prices can differ by 10 – 30 % depending on order size, contractual terms, and market dynamics.

What Drives the Price?

Factor Effect on Cost
Order volume Bulk orders (≥ 100 kg) typically get a better unit price.
Purity / Grade Higher purity grades (≥ 99 %) command a premium.
Geographic region Shipping, import duties, and local market competition can shift the price.
Supplier type Specialized API vendors, large chemical distributors, or contract manufacturers may offer different pricing structures.
Supply chain stability Shortages (e.g., due to raw‑material constraints or regulatory changes) can temporarily push prices up.
Regulatory compliance GMP‑certified suppliers (required for pharmaceutical production) usually charge more than non‑GMP vendors.

How to Get an Accurate Quote

  1. Define the exact grade and purity you need.
  2. Specify the intended use (e.g., ophthalmic drops, research, pre‑clinical studies).
  3. Decide on the order size you plan to place initially—many vendors offer a discount schedule.
  4. Request quotes from multiple sources:
    • Large chemical distributors (e.g., Sigma‑Aldrich, Thermo Fisher).
    • Specialized API suppliers (e.g., Pharma, AHS, MedChem Express).
    • Contract manufacturers (they can offer bundled services like formulation or packaging).
  5. Ask about shipping terms, lead time, and any applicable taxes or duties to factor into your budgeting.

Quick Reference Resources

Resource What It Offers
Pharma-API Bulk API prices, supplier contact sheets.
ChemSpider / PubChem Basic physicochemical data and potential vendors.
PharmaIndustry.com Market analysis reports and recent price trends.
FDA’s Orange Book List of approved generic manufacturers (useful for finding licensed suppliers).

Final Thought

While the above table gives you a rough estimate, the safest way to nail down a price is to reach out to at least three reputable suppliers with a detailed purchase request. They’ll factor in your exact needs (purity, quantity, packaging, delivery) and give you a firm quote that reflects the current market conditions.



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