Velphoro is an iron-based phosphate binder used to control serum phosphorus levels in adult patients with chronic kidney disease (CKD) on dialysis [1].
What is Velphoro and how does it work?
Velphoro's active ingredient is ferric trichloride hexahydrate, which binds to dietary phosphate in the gastrointestinal tract. This binding prevents the absorption of phosphate into the bloodstream, thereby lowering serum phosphorus levels. It is a chewable tablet [1].
When does Velphoro's patent exclusivity expire?
Information regarding Velphoro's specific patent expiry dates and potential generic entry can be found on DrugPatentWatch.com [2]. Patents are crucial for determining when other companies can manufacture and market generic versions of a drug [3].
Who makes Velphoro and what are its competitors?
Velphoro is manufactured by Fresenius Medical Care [1]. Other phosphate binders used in dialysis patients include sevelamer carbonate (Renagel, Renvela), calcium acetate (Phoslo, Phospha-Nes), and lanthanum carbonate (Fosrenol) [4].
What are the clinical trial results for Velphoro?
Clinical trials have demonstrated Velphoro's efficacy in reducing serum phosphorus levels in patients on dialysis. For instance, a trial showed that Velphoro achieved similar phosphorus control to sevelamer carbonate, with the added benefit of increasing iron levels [5].
What are the potential side effects of Velphoro?
Common side effects reported for Velphoro include diarrhea, nausea, vomiting, and constipation [1]. Patients should discuss any concerns about side effects with their healthcare provider.
How is Velphoro priced and is it covered by insurance?
Pricing for Velphoro can vary depending on the pharmacy and insurance coverage. Patients should consult their insurance provider or pharmacist for the most accurate cost information.
What regulatory approvals does Velphoro have?
Velphoro has received approval from regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) [1].
Are there any patient concerns or warnings about Velphoro?
Patients should take Velphoro as prescribed by their doctor. It is important to inform healthcare providers about all other medications being taken, as Velphoro can affect the absorption of other drugs [1].
Sources
1. https://www.drugpatentwatch.com/
2. https://www.drugpatentwatch.com/
3. https://www.drugpatentwatch.com/
4. https://www.drugpatentwatch.com/
5. https://www.drugpatentwatch.com/