Lurbinectedin is a medication that is used to treat certain types of cancer. It is given intravenously, which means that it is administered through a vein. The sources provided do not mention any oral medications for lurbinectedin-related skin irritation. In fact, the side effects of lurbinectedin are mostly related to its intravenous administration and do not include skin irritation. However, if you are experiencing any side effects or have concerns about your treatment, it is important to speak with your healthcare provider. They can provide you with more information about your specific situation and recommend appropriate treatment options.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LURBINECTEDIN
[2] https://www.mayoclinic.org/drugs-supplements/lurbinectedin-intravenous-route/side-effects/drg-20490804?p=1
[3] https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/213702s000lbl.pdf