Ranitidine 300 mg uses?

Ranitidine 300 mg is an H2-blocker that reduces stomach acid. Historically, a 300 mg dose was used for several indications. Common uses (in adults) included:

- Duodenal ulcers and gastric ulcers (to promote healing and relieve pain)
- Gastroesophageal reflux disease (GERD) and erosive esophagitis
- Maintenance therapy to prevent recurrence of ulcers or GERD symptoms
- Pathologic hypersecretory conditions (e.g., Zollinger-Ellison syndrome) with higher or more frequent dosing

Typical dosing patterns (for reference, not a substitute for medical advice):
- GERD/erosive esophagitis: 150 mg twice daily or 300 mg at bedtime (some regimens use 300 mg twice daily)
- Duodenal ulcer: 150 mg twice daily
- Gastric ulcer: 150 mg twice daily
- Zollinger-Ellison syndrome: higher, individualized dosing (often multiple doses per day)

Important current note: Ranitidine has been recalled or withdrawn in many countries due to concerns about NDMA contamination. It’s largely being replaced by alternatives such as famotidine, nizatidine, or proton pump inhibitors (e.g., omeprazole, pantoprazole). If you were prescribed 300 mg ranitidine, consult your clinician for an updated plan or a safer alternative.

If you tell me your country or region, I can give you the current status and alternatives available locally. And if you have symptoms or a health condition, please discuss with a healthcare professional.