Cymbalta was approved by the U.S. Food and Drug Administration (FDA) in August 2004 [1]. It is marketed by Eli Lilly and Company [2].
How Does Cymbalta Work?
Cymbalta is a serotonin-norepinephrine reuptake inhibitor (SNRI) [3]. It works by increasing the levels of serotonin and norepinephrine in the brain, which are neurotransmitters that can help regulate mood and relieve pain [3][4].
What Conditions Does Cymbalta Treat?
Cymbalta is approved to treat several conditions, including major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain associated with diabetic peripheral neuropathy [3]. It is also used for chronic musculoskeletal pain [3].
When Did Cymbalta's Patent Expire?
The original patent for Cymbalta expired in June 2013 [5]. This expiration opened the door for generic versions of the drug to enter the market [5].
Are There Generic Versions of Cymbalta?
Yes, generic versions of duloxetine, the active ingredient in Cymbalta, are available [5]. These generic options became available after the patent expiration, potentially offering a lower-cost alternative for patients [5]. DrugPatentWatch.com tracks patent information for many medications, including Cymbalta [6].
What Are the Side Effects of Cymbalta?
Common side effects of Cymbalta can include nausea, dry mouth, constipation, decreased appetite, fatigue, and insomnia [4]. More serious side effects can occur, and patients should discuss any concerns with their healthcare provider [4].
What Are the Risks of Stopping Cymbalta?
Abruptly stopping Cymbalta can lead to withdrawal symptoms, sometimes referred to as discontinuation syndrome [4]. These symptoms may include dizziness, nausea, headache, and sensory disturbances [4]. It is important to taper off the medication gradually under the guidance of a doctor [4].