Yes, Wegovy Is a Once-Weekly Injection
Wegovy (semaglutide) is administered as a single subcutaneous injection once every week. Patients typically take it on the same day each week, with or without food, and can adjust the day if needed as long as at least 48 hours pass since the previous dose.[1]
How to Use Wegovy Step by Step
Start at 0.25 mg once weekly for the first 4 weeks to minimize side effects, then increase gradually every 4 weeks (0.5 mg, 1 mg, 1.7 mg) up to the maintenance dose of 2.4 mg once weekly. Use the pre-filled pen, inject into the abdomen, thigh, or upper arm, and rotate sites.[1][2]
What If I Miss a Dose?
Inject as soon as possible within 5 days of the missed dose. If more than 5 days have passed, skip it and resume your regular schedule. Do not double up.[1]
How Wegovy Compares to Ozempic Dosing
Both are semaglutide and dosed once weekly, but Wegovy goes up to 2.4 mg for weight loss, while Ozempic maxes at 2 mg for diabetes. They're essentially the same drug from Novo Nordisk, just branded differently.[2]
Common Patient Questions on Timing and Storage
Store pens in the fridge until first use; after that, keep at room temperature for up to 28 days (avoid freezing or direct sunlight). Each pen holds 4 weekly doses. No data shows benefits from more frequent dosing—once weekly mimics the drug's long half-life of about 1 week.[1][2]
[1]: Wegovy Prescribing Information (Novo Nordisk)
[2]: FDA Label for Wegovy