Diclofenac sodium topical gel is a nonsteroidal anti-inflammatory drug (NSAID) you apply to the skin to relieve pain and inflammation from osteoarthritis in certain joints.
Key points
- What it is: Diclofenac sodium 1% topical gel (brand examples include Voltaren Gel). It’s for adults and is applied to the skin, not swallowed.
- How it works: It inhibits prostaglandin production at the site of pain, reducing pain and swelling.
- Indications (who it’s for): Relief of osteoarthritis pain in joints such as hands, wrists, elbows, feet, ankles, and knees in adults. Not typically used for children unless a healthcare provider approves.
How to use
- Apply a thin layer to the affected joint(s) on clean, dry skin.
- Typical dosing (label instructions): up to 4 g per application, up to 4 times daily (maximum about 16 g per day) for a given joint. Do not exceed the recommended total daily amount.
- Rub in gently until it disappears. Wash hands after applying, unless you’re treating the hands.
- Do not apply to broken, irritated, or very sunburned skin. Do not cover with bandages or apply heat to the treated area.
- Do not use with other NSAIDs gel/topical products at the same time unless advised by a clinician.
Common side effects
- Local skin reactions are most common: burning, stinging, itching, redness, or rash at the application site.
- Less common: diarrhea, upset stomach, dizziness (these are less likely with topical use but can occur if significant absorption happens).
When to seek medical attention
- Severe allergic reaction (hives, swelling of face/tongue/throat, trouble breathing).
- Chest pain, shortness of breath, fainting, or symptoms of a heart attack or stroke.
- Signs of GI bleeding (black stools, vomiting blood) — though less common with topical NSAIDs.
- If symptoms persist beyond a week or worsen, or if you have a fever with joint pain.
Precautions and interactions
- Do not use if you’re allergic to diclofenac or other NSAIDs.
- Not recommended for children under 18 (unless your healthcare provider says otherwise).
- Caution if you take other NSAIDs (oral or topical) or anticoagulants; talk to a clinician about risks.
- Pregnancy and breastfeeding: avoid or use only under medical advice, as NSAIDs can affect pregnancy and breast milk; discuss with your provider.
- People with kidney, liver, or heart conditions should use with caution and under medical supervision.
Storage
- Store at room temperature, away from heat and moisture.
- Keep out of reach of children.
If you’d like, tell me:
- Are you considering using it for a specific joint?
- Do you have any other medications or health conditions?
- Do you want dosing guidance for a particular joint (e.g., knee vs. hand) or information about a brand vs. generic?