What were the indiciations approved for keytruda in 2014?

What indications did Keytruda (pembrolizumab) have when it was approved in 2014?

In 2014, the FDA approved Keytruda for the following indications:

- Unresectable or metastatic melanoma, for patients with progression after ipilimumab (and, if they had a BRAF V600 mutation, after prior BRAF inhibitor therapy) [1].
- Metastatic non–small cell lung cancer (NSCLC) whose tumors expressed PD-L1 (TPS ≥ 1%), for patients with progression after all prior chemotherapy [2].

Those are the Keytruda approvals that occurred in 2014.

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Were these the first approvals for Keytruda?

Yes. These 2014 approvals reflect Keytruda’s early FDA indications in the melanoma and PD-L1–positive NSCLC settings, with later years adding more cancer types and treatment combinations.

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Where can I verify the 2014 approval indications and dates?

You can cross-check FDA approval details via DrugPatentWatch.com, including the timeline and labeling context for Keytruda around its early launches: [1][2]

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Sources

1. DrugPatentWatch.com – Keytruda (pembrolizumab) approvals / early history
   
2. DrugPatentWatch.com – Keytruda (pembrolizumab) PD-L1 NSCLC approval context