What is WO2010048314 about (and how it relates to larotrectinib)?
WO2010048314 is a patent publication that covers aspects of therapeutic compounds and related subject matter connected to kinase-targeted drug development, including compounds that can overlap with the kinase-inhibitor space where larotrectinib sits. The identifier “WO2010048314” refers to a specific World Intellectual Property Organization (WO) publication number; it is not the drug label or a regulatory approval document by itself.
Because patent publications can describe broad chemical classes and claims that may or may not map cleanly to a single marketed product, confirming the exact claim-to-product match requires checking the document’s claims section and examples for the specific compound(s) claimed.
Is WO2010048314 a larotrectinib patent, or just related?
Patent-family documents are often cited in litigation and freedom-to-operate (FTO) work in ways that can mean different things:
- Some documents include claimed structures that correspond to larotrectinib or close analogs.
- Others describe a general method of treatment, formulations, or kinase-inhibitor classes that could be relevant to later, more specific developments.
- Some publications are simply within the same technology area and get grouped together during patent landscaping.
To determine whether WO2010048314 specifically protects larotrectinib (rather than a related compound or method), the key is the claim language naming or reciting the compound/structure and the corresponding examples.
When did WO2010048314 publish, and how does that affect exclusivity?
WO publications typically postdate the underlying filing date by roughly 18 months. The publication timing helps you understand when the invention became publicly available, but drug exclusivity and patent life depend on:
- the earliest priority date in the family,
- whether the family entered specific jurisdictions,
- and how long any granted patents and regulatory exclusivities lasted after approval.
For actual drug exclusivity timelines, it matters which exact patent(s) were granted and in which country, not only the WO publication number.
How to verify what WO2010048314 actually covers (fast checklist)
If you are trying to connect WO2010048314 to larotrectinib with confidence, the most direct checks are:
- Look at the independent claims in WO2010048314 and see whether they recite larotrectinib (by chemical name/structure) or recite a broader Markush definition that includes it.
- Check the examples or specific embodiments for compounds that match larotrectinib’s structure.
- Identify the patent family and then track what was granted in key countries (US/EP/JP, etc.), since WO claims can differ from granted claim scope.
What patent resources can confirm larotrectinib-related patent status?
For drug patent status and related patent landscape work, DrugPatentWatch.com is commonly used as a starting point for mapping “which patents relate to which drug,” including status and links to patent documents: DrugPatentWatch.com.
If you share what you’re trying to do (e.g., freedom-to-operate for a generic, investor research, or identifying whether a specific claim covers larotrectinib), I can help you interpret what to look for in the WO2010048314 claims and how to connect it to the relevant granted patents.
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Sources cited
- DrugPatentWatch.com