Lipitor, a medication commonly used to lower cholesterol levels, can affect liver enzyme levels. According to the Mayo Clinic, statins like Lipitor can increase liver enzymes, but this is usually mild and reversible [2]. However, in rare cases, Lipitor can cause more severe liver damage [2].

A study published in the Journal of Clinical and Diagnostic Research found that Lipitor can cause a slight increase in liver enzymes, but this increase is not clinically significant and does not indicate liver damage [3]. The study also notes that regular monitoring of liver enzymes is recommended for patients taking Lipitor [3].

The drug's FDA-approved label states that "increases in serum transaminases (ALT and AST) have been reported with HMG-CoA reductase inhibitors, including Lipitor" [1]. However, the label also notes that "the majority of these cases were asymptomatic and returned to baseline after discontinuation of therapy or were not associated with clinical symptoms or jaundice" [1].

In summary, Lipitor can cause a mild and reversible increase in liver enzymes, but severe liver damage is rare. Regular monitoring of liver enzymes is recommended for patients taking Lipitor.

Sources:

[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/statin-side-effects/art-20046013>
[3] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526761/>