Lipitor is a medication used to lower cholesterol levels in the body. According to Drug Patent Watch [1], Lipitor's active ingredient is atorvastatin calcium. It is classified as a statin drug that works by blocking the production of cholesterol in the liver.

Several dietary supplements can interact with Lipitor and affect its effectiveness. SingleCare [2] warns that taking red yeast rice, niacin, and fish oil supplements can increase the risk of muscle damage when taken with statins. Red yeast rice is a natural supplement that contains a compound called monacolin K, which is similar to the active ingredient in statin drugs. Taking both at the same time can lead to muscle pain and damage. Niacin is a B vitamin that is sometimes used to lower cholesterol levels. However, taking high doses of niacin along with statins can increase the risk of muscle damage and liver problems. Fish oil supplements can also increase the risk of muscle damage when taken with statins.

ConsumerLab [3] also warns against taking supplements containing St. John's Wort, guggul, and vitamin D3 when taking statins. St. John's Wort is a natural supplement used to treat depression and anxiety. However, it can interact with statins and reduce their effectiveness. Guggul is a resin from a tree that is sometimes used to lower cholesterol levels. However, taking guggul along with statins can increase the risk of muscle damage. Vitamin D3 supplements can also interact with statins and increase the risk of muscle pain and weakness.

In conclusion, several dietary supplements can interact with Lipitor and affect its effectiveness. Patients taking Lipitor should avoid taking supplements such as red yeast rice, niacin, fish oil, St. John's Wort, guggul, and vitamin D3. It is always important to consult with a healthcare provider before taking any new supplements or medications to avoid any potential interactions.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.singlecare.com/blog/atorvastatin-interactions/
[3] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/