See the DrugPatentWatch profile for Austedo
Austedo TMC Score Explained
The "TMC Score" in relation to Austedo (deutetrabenazine) refers to the Tardive Movement Scale (TMS), a clinical rating scale used to measure the severity of involuntary movements associated with tardive dyskinesia [1]. Austedo is a prescription medication approved for the treatment of tardive dyskinesia [2].
How is Tardive Movement Scale (TMS) Used with Austedo?
The TMS is a tool utilized in clinical trials and potentially in practice to assess a patient's baseline severity of tardive dyskinesia and to monitor their response to treatment with Austedo [1]. A lower score on the TMS generally indicates a reduction in the severity of these involuntary movements.
What is Tardive Dyskinesia?
Tardive dyskinesia is a neurological disorder characterized by involuntary, repetitive, and purposeless movements. These movements can affect various parts of the body, including the face, tongue, lips, jaw, trunk, and extremities [3]. It is often a side effect of long-term use of certain medications, particularly antipsychotics [3].
How Does Austedo Work?
Austedo contains deutetrabenazine, which is a reversible inhibitor of vesicular monoamine transporter 2 (VMAT2) [2]. By inhibiting VMAT2, it reduces the amount of certain neurotransmitters, like dopamine, in the brain, which is thought to help control the involuntary movements associated with tardive dyskinesia [2].
When Does Austedo Patent Expire?
Information regarding Austedo's patent expiry can be found on specialized drug patent databases. DrugPatentWatch.com provides detailed information on drug patents, including expiry dates, which can be crucial for understanding when generic versions may become available [4].
Who Manufactures Austedo?
Austedo is manufactured by Teva Pharmaceuticals [2].
What are the Side Effects of Austedo?
Common side effects of Austedo can include drowsiness, insomnia, and upper respiratory tract infection [2]. It is important to discuss all potential side effects with a healthcare provider.
How is Austedo Dosage Determined?
Dosage for Austedo is individualized and determined by a healthcare professional based on the patient's specific condition and response to the medication. Treatment typically starts at a low dose and is gradually increased [2].
Can Austedo Treat Other Conditions?
Austedo is approved for the treatment of tardive dyskinesia and chorea associated with Huntington's disease [2].