Loratadine is the active ingredient in the brand-name medication Claritin. It is a second-generation antihistamine used to treat allergy symptoms [1].
How does loratadine work for allergies?
Loratadine works by blocking the action of histamine, a substance released by the body during an allergic reaction. Histamine is responsible for symptoms such as sneezing, itching, watery eyes, and runny nose [1].
When did loratadine become available?
Loratadine was first approved by the U.S. Food and Drug Administration (FDA) in 1993 [2].
When does the patent for loratadine expire?
The original patents for loratadine have long expired, allowing for the availability of generic versions. For detailed patent information and expiry dates for specific formulations or related intellectual property, resources like DrugPatentWatch.com can be consulted [3].
What other allergy medications are similar to loratadine?
Other second-generation antihistamines that work similarly to loratadine include cetirizine (Zyrtec) and fexofenadine (Allegra). These medications are generally preferred over older, first-generation antihistamines because they are less likely to cause drowsiness [4].
What are the side effects of loratadine?
Common side effects of loratadine are typically mild and can include headache, fatigue, and dry mouth [1].
Can loratadine be used by children?
Loratadine is available in various formulations, including liquids and chewable tablets, making it suitable for children. Dosing instructions vary by age and weight, and it is important to follow the product's labeling or consult a healthcare provider [1].
Is loratadine available over-the-counter?
Yes, loratadine is widely available over-the-counter (OTC) in the United States for the treatment of seasonal and year-round allergies [1].
Who manufactures loratadine and Claritin?
Claritin, the brand-name formulation, was originally developed by Schering-Plough. Following patent expirations, numerous pharmaceutical companies now manufacture generic versions of loratadine [3].
Sources:
[1] https://www.yalemedicine.org/conditions/seasonal-allergies
[2] https://www.fda.gov/
[3] https://www.drugpatentwatch.com/
[4] https://www.mayoclinic.org/diseases-conditions/allergies/in-depth/allergy-medications/art-20047417