Lipitor (atorvastatin) is a medication used to lower cholesterol levels in the blood. Antihistamines, on the other hand, are a class of drugs used to relieve symptoms of allergies. There is no significant interaction between Lipitor and antihistamines, and they can generally be taken together without any adverse effects. However, it is important to note that some antihistamines, such as diphenhydramine, can cause drowsiness and may interact with other medications that cause drowsiness, including Lipitor [2]. Patients taking Lipitor should consult their healthcare provider before taking any new medications, including antihistamines, to ensure there are no potential drug interactions [3]. Additionally, it is essential to follow the dosage instructions provided by the healthcare provider and to report any side effects or adverse reactions that may occur [1].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.drugs.com/drug-interactions/allergy-relief-tablets-with-atorvastatin-1486-14544-276-0.html
[3] https://www.verywellhealth.com/statin-side-effects-and-drug-interactions-698202