What are the side effects of Duavee?

What are the most commonly reported side effects of Duavee?

Duavee is a combination of bazedoxifene and conjugated estrogens, used in the treatment of postmenopausal osteoporosis and in the prevention of postmenopausal osteoporosis. According to the [FDA label] (https://www.accessdata.fda.gov/drugsatfdadocs/label/2014/021938s000lbl.pdf), common side effects of Duavee include [1]:

- Vaginal discharge (8.6%)
- Hot flashes (6.4%)
- Headache (5.1%)
- Cough (4.8%)
- Fatigue (4.4%)
- Musculoskeletal pain (4.2%)
- Abdominal pain (3.2%)

What are some rarer side effects of Duavee?

In addition to these common side effects, there are several rarer ones that may be experienced by patients taking Duavee, including [1]:

- Thromboembolic events (e.g., pulmonary embolism, deep vein thrombosis) (0.2%)
- Stroke or transient ischemic attack (0.1%)
- Vertebral fractures (0.1%)
- Endometrial cancer (0.1%)

What precautions should I take when taking Duavee?

Before taking Duavee, it's essential to discuss your medical history, including any previous blood clots or cancers, with your doctor. Patients with a high risk of breast cancer, heart disease, or stroke may not be suitable for Duavee. Additionally, inform your doctor about any medications you're currently taking, especially antacids, anticoagulants, or medications that contain estrogen [2].

Sources:

[1] https://www.accessdata.fda.gov/drugsatfdadocs/label/2014/021938s000lbl.pdf
[2] https://www.drugs.com/dru/Duavee.html