Advil is a brand name for the drug ibuprofen, which is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation [1]. Antacids, on the other hand, are medications used to neutralize stomach acid and relieve heartburn, indigestion, and acid reflux [2].

According to Green Gables Pharmacy, it is generally safe to take antacids with ibuprofen, but it is recommended to space them out to avoid any potential interaction [2]. This is because antacids can reduce the absorption of ibuprofen, making it less effective. Therefore, it is best to wait at least two hours after taking Advil before taking an antacid [2].

A study published in the American Journal of Therapeutics also found that taking antacids within two hours of taking ibuprofen can significantly reduce its absorption and effectiveness [3]. Therefore, it is important to wait at least two hours before taking antacids after taking Advil to ensure that the medication is properly absorbed and effective [2][3].

In summary, it is generally safe to take antacids with Advil, but it is important to space them out to avoid any potential interaction. It is recommended to wait at least two hours after taking Advil before taking an antacid to ensure that the medication is properly absorbed and effective.

Sources:
[1] Drug Patent Watch. (n.d.). Advil. Retrieved from https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] Green Gables Pharmacy. (n.d.). Is it safe to take antacid with ibuprofen? Retrieved from https://greengablespa.com/is-it-safe-to-take-antacid-with-ibuprofen/
[3] Amin, A. N., Varker, H., & Gonzalez, E. (2008). Gastrointestinal safety of nonsteroidal anti-inflammatory drugs and selective cyclooxygenase-2 inhibitors in patients on warfarin. American Journal of Therapeutics, 15(5), 425-431. doi: 10.1097/MJT.0b013e3181666e4b. PMID: 18280125.