Taking Advil with food can help reduce the risk of stomach discomfort associated with nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, which is the active ingredient in Advil. According to guidelines provided by the Hospital for Special Surgery, taking NSAIDs with food or milk can help protect the stomach lining and decrease the likelihood of irritation or ulcer formation. This is supported by Drugs.com, which also recommends taking ibuprofen with food or a glass of milk to help prevent stomach upset. It is advisable to follow these guidelines to minimize the risk of gastrointestinal side effects when taking Advil or other NSAIDs. [2][3]

Sources:
[2] https://www.hss.edu/conditions_guidelines-reduce-side-effects-nsaids.asp
[3] https://www.drugs.com/medical-answers/you-ibuprofen-empty-stomach-3572019/